The aim of this project is to develop an intelligent Bio-inspired self-defending/ self-healing security frame work for IP Multimedia System (IMS) and Next Generation All-IP Networks, which will complement existing authentication and encryption mechanisms to protect infrastructure nodes and subscribers against the attacks launched by malicious nodes in the network. These unique and real-time vulnerabilities which need to be addressed in the IMS network include: IMS framework-related vulnerabilities, SIP protocol vulnerabilities, VoIP/ video/ PoC/ Messaging/ Presence/ Conferencing application vulnerabilities; and voice spam, media plane related vulnerabilities. This framework is expected to become a cardinal component that will protect against the misuse of the network resources of an operator. The goal is that our system will ultimately become integral part of security for IMS and Next Generation All-IP networks.